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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '122cb078b9f73f706635af55a5622049a6640a1832835fcf3d4282257a647da6' 
  AND token = 'NfJIk2oQDhxfG63tgMTJVzBf7jjRPD63dPadNfEm6RU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}