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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5618aaee663eac88e4a9ec2f84c9d24d90716043fff778676f091b29bb840ade' 
  AND token = 'U1veasYL8nL584JV3/LFZEZT4qO76GqnV25/z6QPz7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}