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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50d3dc12b864d553819952d08197d0b09d61e7c7b30d4193c1115e199fbc68fa' 
  AND token = 'CGVW+dlc1E2h2Lgc+Aq+lnxf5FSHXftQ5LRgqRc9PTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}