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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b443a32636664e65cd259149c742c86b9fc0d54a5db7d36da69e95ae2af9ba0b' 
  AND token = 'NAFyUBXjph1Y8aFTSao1SrXYN78SLc2HW+uppZujOK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}