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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86ddd687cb84c08e746eb28892b219fe1478027f505ad5d3d315a5db07623333' 
  AND token = '4oXtVcBb4sBp4flaDmMcbWlejTYaeAW49c8nYUt6Qv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}