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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2246c354e0cc88a99d31c975ac27493311eee89256e7fe618af931da3d2189a7' 
  AND token = 'J+xM1oIxm7tr3Nvrs0Lrf6CwC+cLjEYhCZtlsWvXWXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}