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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a614e230e118b6df609bbdeac546f53b39b416996c13fba0eb7a190e3664e87f' 
  AND token = 'VMi4tXg+Z7Jn2RcYp7A74sBV4yQ8hxW33A7ynyPSThk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}