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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72642e76e772a90d99f188da64ab0c531ecd00278e8dae567c5df7abc01f1118' 
  AND token = 'pMuWwcv8yt2p0U8sFcuf4hNG8eMjwp7zLqIvUBTCfnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}