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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8419cff2def621213a7626262d76606e1a264b9c701ebe24450ab7eb9837cdf3' 
  AND token = 'SuRgU2s2Y7n2M7EqtCr7NVeNT+hj9p2R1pzS56DdwFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}