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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52b2b9dd639cfc91d4b3147e88ae33155d0b112a019332669172ec7a3e18bbfc' 
  AND token = 'X7K5H5KmbBeVNTMxZ3NFlsIEwq8jdcC1kfxlWHoz3E0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}