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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8fdf41d120fde31a403c2bc78838ff34efc82be1b7e015937460353d1ac236c' 
  AND token = 'pj09aAzUQS8U9c+NG2pyQOmiu+2SbbkT4/cKSh7VcUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}