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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdf2deaee678793595b9e4727aeb51e385ead77e165454ec83b974356deef4cc' 
  AND token = '+GmBKcbZH0QiALOa50TIl73RKDcQE/jAL3HBMeJK//g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}