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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '462a0c469d7a3ef8ab2ea072e14fbe0924f0c5f8cdc83f7266edd616bd165bd5' 
  AND token = 'DBiLs6ot4VB3hJl8RzlGh8cb78QqPde48l2aUsaCsIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}