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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c22bb2fe885a0fc605e9c6ae70dd47e8975e6cb24441ed7c79835524ef232bc' 
  AND token = 'odpst8EH3VvoAdPPCWIxtQrm0DY4o2TiYCxNQHcWSgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}