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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aba21e5baa1571aa9e1a60191bb69af3a60b4dbdc6370a72b34fab2c546e91f0' 
  AND token = 'JCoQL9sYZypnvMG8+kCLqMdhf2A6kiMwtGjCxQtxQEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}