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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8ed682c7a9e5825c48976cf85396103a6b35abda0782c8b43bbaf735bdb5e2e' 
  AND token = 'rMYtBh/ohrRbjgGbAx7fgKiC3b6cBls+C0Nn3YcrI/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}