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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ef5d147eb99f8e6a6486792f66ba1fba49ff78694e171e61f2269d9706bb10a' 
  AND token = '3wPYAi9d/Ji/sq7Cva+82iTz4+Dd/SIiIY447/F63zg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}