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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0306848d493fef9ee8ff656f8adc877abc927c1fcba267b35642de264606493' 
  AND token = 'VT/PcrIO37J7QZJTtfph8s3T8p1gnMd49GmwpR/HY7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}