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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25a077f50a753508cd3662ae65450d48a63564185919721440b01bac93e0b148' 
  AND token = 'VpO9kaJaUqhy7ADxYpbtz0JMX2V1kfGRxoHKJq8nGLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}