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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3a2b8ac7fe146d65583c810430a4d793671fdc87b1922c00c45eeba3af4c4e1' 
  AND token = 'aBIpEVbT+jrHZShp/y6nRPf8YxQpIlWMyPVB60mdx3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}