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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4574b74b0d6f1f7e09597ebfb3585067b46508c42ac39b5bd949a67cd934215a' 
  AND token = 'wQfhBsj+rZ3Y+PPla0uPCyD84DzB6m6iO6cF8b0Wjws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}