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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e43e6e2b3f2d51805097ed1334f3f8509fdece3b9117d7e77cc829126e14e71' 
  AND token = 'gS9rGJtmasq8khsb2ofa6sSfqtCmeFFv2xI7zii1Bkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}