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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6af4c202983f68e5c73acc6dc609e1d9939e5e89ed51a3975a396f75f396524' 
  AND token = 'wwyvaUks6BhyPhS0p1hc4hcCHZmf2GwbU175/3IoczU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}