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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '519821f44ee39f8ff04eb73c501dc49203c8a303c43c3e0807d3d1c7527c5cf3' 
  AND token = 'AGyKoYPl98hy6xdiEk5a9RMBHYHoNmrn+uKsKtNXuOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}