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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d255f475c7bd0e309fe778d47736dcb26db1a104d0c8ba6bd617e91017029f9' 
  AND token = 'I5dUeNsP90dGPRn/G3k8Rx/Ls8SshSzoAE2yIk3dTlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}