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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '433280f9ebc0a20d196462460ea01e179c7fcd6460a7d33228b2c54b672dade3' 
  AND token = '8SdC7Z9u1XbLpMYUg9oCFtoWdAuFR0EX8kQB2zGzYDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}