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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '460d7eaeece259711301ab89b2c3d076c68b7c1280b232de6802375933b39a48' 
  AND token = '+5Kdo+G98eSUnmVL36FMgaIkvisJXEEiN4TeUqHOQao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}