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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3784a52460e6430387e1b03390592163047f1e51cdb3000ce17427c22da692fe' 
  AND token = '++BkjxkXPLQjxC/9cyvpgeMQKDwOGcg3KaBf3ouX3LE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}