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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '358636afbe9f6ebb0a5a22a1b30495a553aa66dda424713aa3b1c2d4d9804493' 
  AND token = 'aCrVov8dVEHe9Ng2oSfRznA2IeWdyhPNFohb3MZ1Bl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}