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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e04c3468c352fc48e18d06e1325eebe459c8d3e242fb6a17f3d0df423722502' 
  AND token = '3JW8SZ7d34IN3LHGxYOk4qapX3QDnqrWyUMS4QcszqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}