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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ef06bbde76c361fef5689b47b5423941b9270ed07b3354940ad7354f14d8f96' 
  AND token = 'OZxj1yZ3YLeM/ruJ3EWgZ6AYFWjeicErnhHn9q3G1Ms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}