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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f88845a333f9022d169cae0e1e809bd8c58c33de2c5084a3e4c83956b2002cf' 
  AND token = 'dsG2Z0SO0E8nuYKuRee0CdJ0tpwSGal3CgnbQVuTyac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}