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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec6a49a25899382d7e33235b68257413e607cd09a3ffc5a5e2b47e1df7ff9f8c' 
  AND token = 'UDMB5Y9oEzzTPFtbPonhsS2c4z1yeYpucqAE/gqtuYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}