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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37f300728f0c57bad143a30fcbf7cf3c80b435935bea6ae28130e58b98381833' 
  AND token = '7t7jhIyG6Waw/DaTJwOKpuaNoJ5XKMt4SoGt9kr4lB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}