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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd225d8296e9f239e7daa3e6a8d8250a9a8e21b9190db469e005ffd28ad34df4d' 
  AND token = 'Tm/sjNm+r9N/sVCD7z4MmK1t9+RkDi8b29uepJVelIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}