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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '866aed472b762c3d95a2cbf27ba4200d0ed5c67471333cd23bcb5b78b32747a7' 
  AND token = 'Zksu9JcF8fte7hlOLSK7rDJtggIDtSnWF0ziTuT6OhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}