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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40a9b58c053971d89f8c217f3a0694f83fa54fb1a0c601ce2ee86f27ab11e184' 
  AND token = '86NaiDQqqDnZVUzeE6wa0j0cqtu2D1/aiU8YPWOuhRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}