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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '350def5a4172e1b6651c20c880c7348b004925972f21a4b6a14ec9f43a0ec61b' 
  AND token = 'W7Ue9mmH+UoB9EktEa9bzaa0aazkzvbblHu6OkH//V0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}