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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e64f993f9c78a31e12cde633a5d06a34bba83bde7acc98bb46bf2bc0a2634c48' 
  AND token = 'br9cIk3hccgKwhwXShmjI/4uqRkA1Yctctz78vyYndE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}