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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c10622b9f4d18df48794d0f15f3816bf8f446366ac3e1ad73ec974037fd69e4' 
  AND token = 'K42gls0eTgM8MipcWgBCb8YQe+FKnxEEJ6NKsJIr1GU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}