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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a1e7339e4c00531656e99d6045daf6e37fea69d2b7ce9d3394f5d1b1e752c1f' 
  AND token = '3nQiHfpSS+W31qTCYFdz3TGgGOJXA3UJAQv4nWv0XVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00090

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}