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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '087b68808a30e4e41fa15e3ba43d6ac6a25c4e317d9c56608d1071861b7876a2' 
  AND token = 'thZE4WpIIIp+DCRLcAiIOAgDU2iWj5Gwkr+qP8zajcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}