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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66955c9084904ebfb2306ad56b5ff71f2a1ad0b42abe86c504671616a32d4125' 
  AND token = 'N8bGhILGBijKUk9T3duKEv+r3DRiv4LCy+6wKRGeO2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}