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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac4388c002724a3207d87188592b93ee3b5e97d084e1910f473f8b356ed216f4' 
  AND token = 'eIZ5+56z8WAbXX+WjWGMDj4fa3BP4KsYKQobINOb9H0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}