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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '429e23de294effd9fed615a4ce06aa8945df61cdb9bc91969ea95655d9ecf6ad' 
  AND token = '73CSkNZEs+zh3Wwu0g4ioB6ROrYGtr2g10mU7wugxW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}