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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5563f560b2960b728486d0e04d761a8a3afba2f42a9a2c2a8634f22ea6807de2' 
  AND token = 'J1H1idd4VpuwwQcHQx4SmvnZZ1v2czGM6MpGdjp6muQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}