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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e7c6170ef5645b1a8754aff87494f9fcb32c7eddd9d8bbbf0257be6ec90c891' 
  AND token = 'bL3xTu6pzUdc4bpi1XODSpPOoG50WR0Mr+25WKArGOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}