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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29cc9be6a4c8e200062f4219ce56834100004c1f3683b8cc130e6d5c35d282da' 
  AND token = 'awPui9yy9tsILoi+zDVfkF6Y147QShwlclQLxU3Qrmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}