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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45b3b90508fd29d47c259ae593390f8234a3f0e5f99dbf2e3e3a246060dd59f8' 
  AND token = 'rlzuRc36BseLsqjvaJOKMjjN8Dk3lgBkfcTUMOi2kjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}