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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ef52ce3a2a1888729f0143d314a82762e23234048336a5217c3d34fb3c36bb6' 
  AND token = 'SLHnpWGpWHwS1OL6YGAuXdw0DHSVd/9enoFooKBgzYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}